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MOTS-c More energy, from the cell up

MOTS-c — the peptide studied in the mitochondria.

  • Steadier energy through the day
  • Studied for its role in glucose metabolism
  • Acts where the body makes energy, not on appetite
  • Ashley, a PeptoClinic customer, with the order they received
  • Brandon, a PeptoClinic customer, with the order they received
  • Emily, a PeptoClinic customer, with the order they received
  • Jessica, a PeptoClinic customer, with the order they received

Customers

$130 $160

10 mg Vial (Lyophilized)

  • Physician consult & prescription review Free
  • Bacteriostatic water · 10 ml Free

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MOTS-c 10 mg vial — lyophilised peptide, ≥99% HPLC

What the research says

MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial genome. Research examines its role as a regulator of metabolic homeostasis, with documented interest in AMPK activation, glucose utilisation assays and exercise-response models. The peptide was described by Lee et al. (Cell Metab 2015). It has not received FDA approval, and it is on the FDA's list of bulk substances that compounding pharmacies may not use.

Published studies

Each link opens the original record on PubMed or the public trial registry.

Purity
≥99% HPLC
Presentation
10 mg Vial (Lyophilized)
Research area
Metabolic research
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Made for everyday use

  • Steadier energy through the day

  • Studied for its role in glucose metabolism

  • Acts where the body makes energy, not on appetite

  • Packaging

    Discreet boxes with the lyophilised vial sealed inside. As a powder it travels stable at room temperature, so no cold chain is needed.

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A physician reviews your case before anything ships.

  • Secure checkout
  • Physician-reviewed
  • ≥99% HPLC
  • Packaging

Also known as: MOTSc, mitochondrial ORF of the 12S rRNA type-c

Metabolic research ≥99% HPLC Sizes available: 10 mg – 20 mg Physician-reviewed

Documented research areas

  • AMPK activation
  • Glucose utilisation
  • Mitochondrial signalling

MOTS-c specifications

MOTS-c — supply specification. Supplied after a physician reviews your consultation.
Property Specification
Classification Mitochondrial-derived peptide, 16 aa
Also known as MOTSc, mitochondrial ORF of the 12S rRNA type-c
Purity ≥99% HPLC
CAS number 1627580-64-6
Molecular formula C101H152N28O22S2
Molecular weight 2174.6 g/mol
Vial sizes available 10 mg, 20 mg
Intended use Supplied after physician review — not an approved medicine
Physical form Lyophilised powder
Storage -20 °C, protected from light
Reconstitution Bacteriostatic water · 10 ml bottle, included at no charge (one per vial)
Testing HPLC + mass spectrometry, per batch
Dispatch Sealed box, tracked, from Argentina or the United States — no cold chain needed

Published lab reports

The third-party analysis behind this compound, published as the laboratory issued it — their letterhead, their report number, their key.

Certificate of analysis for MOTS-c, issued by Freedom Diagnostics Open the full certificate

MOTS-c

Report #2606220868
Purity
99.33%
Content found
11.17 mg

against a 10 mg label

Laboratory
Freedom Diagnostics

Jun 25, 2026

Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JAGB2606220868

Open Freedom Diagnostics's verification page

Each report covers the batch submitted for it and no other. It is evidence about that material rather than a guarantee about every vial ever shipped, which is why these are dated, numbered and published one at a time instead of summarised into a badge.

Take the certificates with you

Each report as a PDF, the whole page exactly as the laboratory issued it. For a purchasing file, a colleague, or a batch record.

  • MOTS-c 99.33%

    Report #2606220868 · Freedom Diagnostics · PDF

    Download PDF

Certificate of analysis

The CoA for the specific batch you would receive is reviewed during your consultation and ships with the material.

Request this batch CoA

Frequently asked questions

How do I know a lot is what it claims to be?

From that lot's certificate of analysis, not from what the supplier asserts. The certificate names the laboratory that took the measurement, the date, the task number, the method and the purity found. PeptoClinic publishes the full reports uncropped, exactly as the laboratory printed them.

What is a certificate of analysis and how do you read one?

It is the report an analytical laboratory issues on a specific sample. Four things are worth checking: which compound it claims to have measured, by what method (HPLC for purity, mass spectrometry for identity), what figure it found, and whether the task number can be verified against the laboratory. A certificate with no verifiable task number is a picture.

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Supplied after physician review — not an approved medicine