Retatrutide Lose the fat, keep the muscle

Retatrutide — steady, muscle-sparing fat loss.

Steady fat loss, week over week
Holds onto lean muscle while you lean out
Cravings and appetite under control

Customers

Most requested

$235 $285

10 mg Vial (Lyophilized)

Physician consult & prescription review Free
Bacteriostatic water · 10 ml Free

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Retatrutide 10 mg vial — lyophilised peptide, ≥99% HPLC

What the research says

Retatrutide is a synthetic triple receptor agonist studied for its simultaneous activity at the GLP-1, GIP and glucagon receptors. In published preclinical and clinical literature it is investigated in the context of energy balance, insulin sensitivity and satiety signalling pathways. Supplied as lyophilised powder for reconstitution. It was developed by Eli Lilly under the code LY3437943. The phase 2 obesity trial (Jastreboff et al., N Engl J Med 2023) and the phase 3 obesity trial (Jastreboff et al., N Engl J Med 2026) are the main published human data. Retatrutide has not received FDA approval and is not sold under any brand name.

Published studies

Each link opens the original record on PubMed or the public trial registry.

Purity: ≥99% HPLC
Presentation: 10 mg Vial (Lyophilized)
Research area: Metabolic research

Made for everyday use

Steady fat loss, week over week
Holds onto lean muscle while you lean out
Cravings and appetite under control
Packaging

Discreet boxes with the lyophilised vial sealed inside. As a powder it travels stable at room temperature, so no cold chain is needed.

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Physician-reviewed
≥99% HPLC
Packaging

Also known as: LY3437943, Reta, triple agonist GLP-1/GIP/glucagon

Metabolic research ≥99% HPLC Sizes available: 10 mg Physician-reviewed

Documented research areas

Energy balance
Satiety signalling
Insulin sensitivity

Retatrutide specifications

Retatrutide — supply specification. Supplied after a physician reviews your consultation.
Property	Specification
Classification	Triple GLP-1 / GIP / glucagon receptor agonist
Also known as	LY3437943, Reta, triple agonist GLP-1/GIP/glucagon
Purity	≥99% HPLC
Vial sizes available	10 mg
Intended use	Supplied after physician review — not an approved medicine
Physical form	Lyophilised powder
Storage	-20 °C, protected from light
Reconstitution	Bacteriostatic water · 10 ml bottle, included at no charge (one per vial)
Testing	HPLC + mass spectrometry, per batch
Dispatch	Sealed box, tracked, from Argentina or the United States — no cold chain needed

Published lab reports

The third-party analysis behind this compound, published as the laboratory issued it — their letterhead, their report number, their key.

Retatrutide

Report #2610220370

Purity: 99.83%
Content found: 10.62 mg
Laboratory: Freedom Diagnostics

Certificate of analysis for Retatrutide, issued by Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JBL2610220370

Open Freedom Diagnostics's verification page

Retatrutide

Report #2610220372

Purity: 99.89%
Content found: 20.36 mg
Laboratory: Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JBL2610220372

Open Freedom Diagnostics's verification page

Retatrutide

Report #2609290762

Purity: 99.9%
Content found: 24.11 mg
Laboratory: Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JBL2609290762

Open Freedom Diagnostics's verification page

Retatrutide

Report #2608120314

Purity: 99.83%
Content found: 12.28 mg
Laboratory: Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JAGB2608120314

Open Freedom Diagnostics's verification page

Retatrutide

Report #2607150672

Purity: 99.93%
Content found: 16.2 mg
Laboratory: Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JAGB2607150672

Open Freedom Diagnostics's verification page

Retatrutide

Report #2607150683

Purity: 99.94%
Content found: 22.36 mg
Laboratory: Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JAGB2607150683

Open Freedom Diagnostics's verification page

Retatrutide

Report #2606220866

Purity: 99.86%
Content found: 12.02 mg
Laboratory: Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JAGB2606220866

Open Freedom Diagnostics's verification page

Retatrutide

Report #2606110705

Purity: 99.95%
Content found: 11.69 mg
Laboratory: Freedom Diagnostics

Open the full certificate Verify at the lab

Checked with this key on Freedom Diagnostics's own verification page: JAGB2606110705

Open Freedom Diagnostics's verification page

Each report covers the batch submitted for it and no other. It is evidence about that material rather than a guarantee about every vial ever shipped, which is why these are dated, numbered and published one at a time instead of summarised into a badge.

Take the certificates with you

Each report as a PDF, the whole page exactly as the laboratory issued it. For a purchasing file, a colleague, or a batch record.

Retatrutide 99.83%

Report #2610220370 · Freedom Diagnostics · PDF

Download PDF
Retatrutide 99.89%

Report #2610220372 · Freedom Diagnostics · PDF

Download PDF
Retatrutide 99.9%

Report #2609290762 · Freedom Diagnostics · PDF

Download PDF
Retatrutide 99.83%

Report #2608120314 · Freedom Diagnostics · PDF

Download PDF
Retatrutide 99.93%

Report #2607150672 · Freedom Diagnostics · PDF

Download PDF
Retatrutide 99.94%

Report #2607150683 · Freedom Diagnostics · PDF

Download PDF
Retatrutide 99.86%

Report #2606220866 · Freedom Diagnostics · PDF

Download PDF
Retatrutide 99.95%

Report #2606110705 · Freedom Diagnostics · PDF

Download PDF

Certificate of analysis

The CoA for the specific batch you would receive is reviewed during your consultation and ships with the material.

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Retatrutide, tirzepatide and semaglutide compared

All three act on the hormones that regulate appetite and glucose. What changes is how many receptors each one activates and how far along its development is. Figures from the published trials, not rounded in anyone's favour.

	Retatrutide	Tirzepatide (Mounjaro, Zepbound)	Semaglutide (Ozempic, Wegovy)
Receptors it activates	Three: GLP-1, GIP and glucagon	Two: GLP-1 and GIP	One: GLP-1
Status	In clinical research (phase 3); not approved in any country	Approved in the United States and other countries	Approved in the United States and other countries
Average weight loss in its reference trial	24.2% at 48 weeks on the highest dose (phase 2, NEJM 2023)	20.9% at 72 weeks on 15 mg (SURMOUNT-1, NEJM 2022)	14.9% at 68 weeks on 2.4 mg (STEP 1, NEJM 2021)
Frequency	One injection a week	One injection a week	One injection a week (an oral version also exists)
Most reported adverse effects	Gastrointestinal (nausea, diarrhoea, vomiting), more frequent as the dose rises; increased heart rate	Gastrointestinal (nausea, diarrhoea, vomiting, constipation)	Gastrointestinal (nausea, diarrhoea, vomiting, constipation)

The percentages come from different trials with different durations and populations: they place each compound, they do not rank them head to head. Sources: Jastreboff et al., NEJM 2023 (retatrutide); Jastreboff et al., NEJM 2022 (tirzepatide); Wilding et al., NEJM 2021 (semaglutide).

Frequently asked questions

How do I know a lot is what it claims to be?

From that lot's certificate of analysis, not from what the supplier asserts. The certificate names the laboratory that took the measurement, the date, the task number, the method and the purity found. PeptoClinic publishes the full reports uncropped, exactly as the laboratory printed them.

What is a certificate of analysis and how do you read one?

It is the report an analytical laboratory issues on a specific sample. Four things are worth checking: which compound it claims to have measured, by what method (HPLC for purity, mass spectrometry for identity), what figure it found, and whether the task number can be verified against the laboratory. A certificate with no verifiable task number is a picture.

Retatrutide Lose the fat, keep the muscle

What the research says

Published studies

Made for everyday use

Documented research areas

Retatrutide specifications

Published lab reports

Retatrutide

Retatrutide

Retatrutide

Retatrutide

Retatrutide

Retatrutide

Retatrutide

Retatrutide

Take the certificates with you

Certificate of analysis

Retatrutide, tirzepatide and semaglutide compared

Frequently asked questions

How do I know a lot is what it claims to be?

What is a certificate of analysis and how do you read one?

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